- Group 1 encompasses idiopathic or hereditary PAH, often linked to genetic mutations.
- Group 2 includes PAH related to left heart disease, which can stem from conditions like left ventricular dysfunction.
- Group 3 covers PAH associated with lung diseases or hypoxemia, commonly seen in chronic obstructive pulmonary disease (COPD).
- Group 4 involves PAH due to chronic thromboembolic events, where blood clots obstruct the pulmonary arteries.
- Group 5 comprises miscellaneous causes, such as systemic disorders like sarcoidosis or metabolic diseases.
Understanding the Venice Classification of Pulmonary Arterial Hypertension